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  SPECIFICATION
HIGH-YIELD EMBRYOLOGY (pb)2000
Author: RONALD W. DUDEK
ISBN: 0781731089
Year: 2000
Publisher: LIPPINCOTT WILLIAMS
Category: EMBRYOLOGY
Series: HIGH-YIELD SERIES
Edition: 1
Format: Paperback
Language: English
 ABOUT THE TITLE
High-Yield Cell and Molecular Biology gives you more of what you need to prepare you for the USMLE Step 1! The information found in this text provides a strong understanding of introductory undergraduate cell and molecular biology which serves as a valuable review resource for the board exam. As part of the High-Yield Series , material is presented in a concise, uncluttered fashion. The sections cover information typically found in a second year molecular biology course such as chromosomal DNA, chromosome replication and DNA synthesis, molecular genetics, gene amplification, inherited diseases and molecular immunology. Well illustrated, this text provides students with a strong foundation to prepare them for more advanced work in cell and molecular biology. It also serves as a great source for course review. Lecturers - Click here to order a FREE Review Copy of this title...
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 TABLE OF CONTENTS
Part 1 Packaging of chromosomal DNA: nucleic acids
the human genome
chromosomes
genes
chromatin.
Part 2 Chromosome replication and DNA synthesis: replication fork
telomere
damage and repair of DNA
clinical importance of DNA repair mechanisms.
Part 3 Genetic recombination: general recombination
site-specific recombination.
Part 4 Transposable elements: mechanisms of transposition
transposable elements and genetic variability.
Part 5 Gene amplification: clinical considerations.
Part 6 Recombinant DNA technology: restriction enzymes
gel electrophoresis
enzymatic method of DNA sequencing
southern blotting and prenatal testing for sickle cell anaemia
isolating a human gene with DNA cloning
polymerase chain reaction (PCR)
producing a protein from a cloned gene
site-directed mutagenesis and transgenic animals.
Part 7 Control of gene expression: mechanism of gene regulation
structure of transcription factors and gene regulatory proteins
clinical consideration - growth hormone deficiency and Pit-1 transcription factor
the "lac" operon
summary.
Part 8 Protein synthesis: transcription
converting an RNA transcription to mRNA
translation
clinical considerations.
Part 9 The nucleolus
organization of the nucleolus
assembly of the ribosome
ultrastructure of the nucleolus.
Part 10 Mutations of the DNA sequence: silent mutations
missense mutations
nonsense mutations
frameshift mutations
translocation mutations
RNA splicing mutations
transposable element mutations
trinucleotide repeat mutations.
Part 11 Molecular genetics: polymorphisms
linkage (coinheritance)
population genetics.
Part 12 Inherited diseases: autosomal dominant inheritance
autosomal recessive inheritance
x-linked recessive inheritance
mitochondrial inheritance
multifactorial inheritance
table of inherited disorders.
Part 13 Multifactorial inherited diseases: definition
example - type 1 diabetes.
Part 14 Proto-oncogenes, oncogenes and anti-oncogenes: definitions
designations
classification of oncogenes
mechanism of action of the "ras" proto-oncogene
anti-oncogenes (tumor-suppressor genes)
molecular pathology of colorectal cancer.
Part 15 The cell cycle: phases of the cell cycle
control of the cell cycle
stages of the M phase.
Part 16 Homeotic genes and anterior-posterior body pattern formation: human homeotic genes.
Part 17 Mitochondrial genes: gene products that are encoded by mitochondrial DNA (mrDNA)
other mitochondrial proteins
mitochondrial diseases.
Part 18 Molecular immunology: the clonal selection theory
the B lymphocyte (B cell)
the T lymphocyte (T cell)
clinical considerations.
Part 19 Receptors and signal transduction: ion channel-linked receptors
G-protein-linked receptors
enzyme-linked receptors
steroid hormone (intracellular) receptors
receptor types
nitric oxide (NO)
receptor-mediated endocytosis
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